Chernobyl-related Bladder Lesions: New Interpretation Required

Evaluation of Sensitivity and Specificity of Urine Survivin As A New Molecular Marker in Diagnosis of Bladder Tumors

Bladder cancer is one of the most common forms of cancers in the world. The current gold standards for itsdiagnosis are cystoscopy and urine cytology. Cystoscopy, a naked eye assessment of the bladder, is invasive, uncomfortable and costly with a great deal of personal variability in its results; while urine cytology has high specificity but low sensitivity, particularly for low-grade les...

Urinary bladder carcinogenesis induced by chronic exposure to persistent low-dose ionizing radiation after Chernobyl accident.

Urinary bladder urothelium as well as cells in the microenvironment of lamina propria (endothelial elements, fibroblasts and lymphocytes) demonstrate a number of responses to chronic persistent long-term, low-dose ionizing radiation (IR). Thus, oxidative stress occurs, accompanied by up-regulation of at least two signaling pathways (p38 mitogen-activated protein kinase and nuclear factor-kappaB...

Pitfalls and Limitations of Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Urinary Bladder Cancer

Adequately selecting a therapeutic approach for bladder cancer depends on accurate grading and staging. Substantial inaccuracy of clinical staging with bimanual examination, cystoscopy, and transurethral resection of bladder tumor has facilitated the increasing utility of magnetic resonance imaging to evaluate bladder cancer. Diffusion-weighted imaging (DWI) is a noninvasive functional magnetic...

Interpretation of Endometrial Lesions and Infertility in Mares

Recent Fukushima nuclear detonation, Chernobyl nuclear fallout, three mile island nuclear accident and atomic bomb explosion – rethinking the effects of nuclear radiations over human health

Background: The earlier Atomic Bomb explosion in Hiroshima and Nagasaki, and three worth mentioning nuclear accidents - detonation at Fukushima Daiichi nuclear plant, Chernobyl nuclear fallout and an accident at Three Mile Island nuclear power plant have made us more worried about the secure exploitation of nuclear energy. The central focus of this paper is to review radiation-mediated health e...